Preliminary Program: AASOG 2019
“Biomarkers for Severity, Disparity, and Therapy in Sarcoidosis: Discovery to Delivery”
The Graduate Hotel, Iowa City, Iowa


Friday, April 12, 2019*

7:30-8:30 Registration and Continental Breakfast
8:30-8:40: Welcome, Introduction, Significance of AASOG 2019 Conference: Alicia K. Gerke, MD, University of Iowa, Chair of Organizing Committee
9:10-9:35: Opening Keynote Speaker: Marc Judson, MD, Albany Medical College: “Issues in Selecting Proper Biomarkers in Sarcoidosis Clinical Trials”.
Session 1 (9:35-10:25):  The Path to Discovery of Biomarkers: Immunobiology and Models in Sarcoidosis
9:35-10:00 Anagha Malur, PhD, East Carolina University: “Murine Models of Sarcoidosis Using Instilled Multiwall Carbon Nanotubes:  What can we learn from Genetic Knock-outs?”
10:00-10:35 Muse Davis, MD, PhD, University of Iowa:  “Modeling Granulomatous Inflammation in the Zebrafish Larva”.

Coffee Break: 10:25-10:35

Session 2: Discovery: Perpetuation of Inflammation in Granulomas: Why Patients Progress.
10:35-11:00:  Deborah Winter, PhD, Northwestern University: “Dissecting the Role of Lung Macrophages in Sarcoidosis Using Genomic Approaches”.
11:00-11:25: Antje Prasse, MD, University of Hannover, Germany. “The NLRP3 Inflammasome and IL-1β Pathway in Granuloma Formation of Sarcoidosis”.
11:25-11:50: Brian O’Connor, PhD, National Jewish Medical Center, “Exploring the Epigenetic and Transcriptional Regulation of CD4+ T-cells in Sarcoidosis.”
11:50-12:15: Andrew Fontenot, MD, University of Colorado, “Search for T-cell Epitopes in Sarcoidosis”.

12:15-1:00pm Lunch and Poster Viewing

 Session 3: Feature Session: Women Mentors in Science: Shaping the Future of Sarcoidosis.
1:00-1:25:  Wonder Drake, MD: Vanderbilt University, “Meaningful Mentorship of the Next Generation of Sarcoidosis Scientists”.
1:25-1:50: Erica Herzog, MD, Yale University: “Setting the Stage: Biomarker Discovery in Sarcoidosis”.
1:50-2:15:  Alicia K. Gerke, MD, Iowa: “Evaluating the Natural History of Sarcoidosis”.
2:15-2:35: Lobelia Samavati, MD, Wayne State University: “Innate Signaling and Adaptive Dysfunction in Sarcoidosis”.

Coffee Break: 2:35-2:50

 Session 4: Novel Imaging Biomarkers for Sarcoidosis Diagnosis and Complications
2:50-3:10. Girish Bathla, MD, University of Iowa: “Magnetic Resonance Imaging in Neurosarcoidosis: Where We Stand and What’s On The Horizon”.
3:10-3:35: Lisa Maier, MD, National Jewish Health: “Lung CT as a Marker for Pulmonary Sarcoidosis: Lessons from GRADS Study”.
3:35-4:00: TBA: “Progress in Imaging of Active Inflammation in Cardiac Sarcoidosis”.
4:00-4:25:  Karin Hoth, PhD, University of Iowa: “Neuroimaging and Cognition in Sarcoidosis: Understanding What Underlies the experience of ‘Brain Fog’”.

4:25-4:55pm: AASOG Presidential Address: Elliott Crouser, MD, Ohio State University
NHLBI and FSR Announcements
Closing for the Day with Dinner Instructions

5-6pm: Closed Session (Executive Committee Meeting)
6:00pm-9:30pm Networking Reception, Dinner and Dessert: Location TBA


Saturday, April 13, 2019*:

6:45-7:50  Junior Faculty Development Breakfast (All Welcome)
                  7:00-7:30: W. Ennis James, Medical College of South Carolina: “Starting your Sarcoid Clinic and Career
                  7:30-7:50: Question/Answer Panel

6:45-8:00:  General Breakfast and Networking

8-8:05: Welcome
Session 5:  Identifying Serum Diagnostic and Prognostic Biomarkers
8:05-8:30: Elliott Crouser, MD, Ohio State University: “Circulating exosomes as a marker of severe phenotypes”.
8:30-8:55: Maneesh Bhargava, MD, University of Minnesota: “Mapping Protein Interactions in Pulmonary Sarcoidosis”.
8:55-9:20: Catherine Bonham, MD, U. of Virginia: “MicroRNAs and Sarcoidosis”
9:20-9:40: Karen Patterson, Germany “Fibrotic Sarcoidosis: Who is at risk, how it happens, and when to treat”
9:40-10:05 Dan Culver, DO, Cleveland Clinic: “Outcomes from the FSR-SARC Patient Registry”.

Coffee Break: 10:05-10:20

10:20-11:20: Session 6: Abstract Winner Oral Presentations (Four 15 minute presentations with discussion)

11:20-12:00: Lunch and Poster Viewing

Session 7: Delivery: Bringing Science to Patient Care
12:00-12:25: Misha Rosenbach, MD, U. of Pennsylvania: “Using Apps in clinical practice and in research”.
12:25-12:50:  Aaron Miller, PhD, U. of Iowa: “Missed Opportunities for Diagnosis of Sarcoidosis: How can we improve?”
12:50-1:15: Nadera Sweiss, MD, U. of Illinois, “Advanced therapies for Sarcoidosis: Going Past 2nd Line Therapies”
1:15-1:40: Courtney Montgomery, PhD, U. of Oklahoma, “Genetics of Sarcoidosis”.

1:40-2:05: Closing Keynote: Bob Baughman, MD, University of Cincinnati, “Role of Physiology, Radiology, Clinical Outcome, and Composite Scoring in Assessing Biomarkers”.

2:05-2:15: Thank You and Closing: Alicia Gerke, MD
Shuttles to Airport